Annamaria Manfio

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OBJECTIVE To assess selected physiological effects of non-invasive continuous positive airway pressure delivered by head helmet (CPAPH), a special interface device designed to completely contain the head of the patient, compared to face mask (CPAPM). DESIGN Randomized physiological study. SETTING University research laboratory. PATIENTS Eight healthy(More)
OBJECTIVE We measured pulmonary edema by thermal indocyanine green-dye double-dilution technique and quantitative computed tomography (CT) in patients with acute respiratory distress syndrome and compared the two techniques. DESIGN AND SETTING Prospective human study in a university hospital. PATIENTS Fourteen mechanically ventilated patients with acute(More)
OBJECTIVE We describe a simplified helium dilution technique to measure end-expiratory lung volume (EELV) in mechanically ventilated patients. We assessed both its accuracy in comparison with quantitative computerized tomography (CT) and its precision. DESIGN AND SETTING Prospective human study. PATIENTS Twenty-one mechanically ventilated ALI/ARDS(More)
OBJECTIVE It is commonly assumed that lung volume at zero end-expiratory pressure (functional residual capacity) is not affected by positive end-expiratory pressure (PEEP) even in presence of alveolar recruitment, and it is often ignored when measuring lung recruitment by pressure-volume curves. Aim of the study was to investigate the effect of PEEP on(More)
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