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PurposeThe purpose of this study is to evaluate the efficacy and safety of intravenous (IV) palonosetron in preventing chemotherapy-induced nausea and vomiting (CINV) in patients with cancer who had… (More)
BACKGROUND The randomized, controlled BOLERO-2 (Breast Cancer Trials of Oral Everolimus) trial demonstrated significantly improved progression-free survival with the use of everolimus plus exemestane… (More)
OBJECTIVE Everolimus (EVE)+exemestane (EXE; n = 485) more than doubled median progression-free survival versus placebo (PBO) + EXE (n = 239), with a manageable safety profile and no deterioration in… (More)
125 Background: BOLERO-2, a phase III study, randomized 724 patients with hormone-receptor-positive metastatic breast cancer, who had recurrence or progression on/after prior nonsteroidal aromatase… (More)
155 Background: The phase III BOLERO-2 study at 18 months' median follow-up showed that everolimus (EVE) + exemestane (EXE) significantly improved progression-free survival (PFS) vs EXE alone in 724… (More)