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Previous randomized, placebo-controlled trials (RCTs) assessing the efficacy of the selective γ-aminobutyric acid (GABA)-B receptor agonist baclofen in the treatment of alcohol dependence have reported divergent results, possibly related to the low to medium dosages of baclofen used in these studies (30-80mg/d). Based on preclinical observations of a(More)
This study was undertaken to investigate the dynamics of the level of randomness in gastric electrical signals. Combined recordings of internal gastric electrical activity (GEA) and electrogastrograms (EGG) were obtained from 16 unconscious dogs and two postoperative patients. The signals were amplified using specially designed amplifiers with flexible(More)
The aim of this study was to examine the reliability of percent distribution of electrogastrographic (EGG) power in recognizing gastric electrical uncoupling. Sixteen anaesthetized dogs underwent laparotomy and implantation of six pairs of stainless-steel wire electrodes. Distal stomach was measured and three sections with approximately equal lengths were(More)
OBJECTIVE The aim of this study was to identify if psychological distress may contribute to treatment outcome in alcohol-addicted patients during a follow-up period of 5 months after detoxification. METHODS As part of a prospective, multicenter, randomized study in relapse prevention, patients' levels of psychological distress were assessed using the(More)
This study was undertaken to investigate the correlation between power dynamics of gastric electrical activity (GEA) assessed with different recording techniques. A total of seven eight-channel 1-hr combined recordings were obtained from three subjects in five consecutive postoperative days. Four channels were recorded from bipolar electrodes implanted into(More)
The diagnosis of cancer, the symptoms of the illness and its treatment have an influence on how patients and their caregivers experience distress. However, data focusing on caregivers and their cancer-related distress in the outpatient setting is sparse. This study aimed to compare cancer-related distress of caregivers and patients and to derive(More)
Current research on Internet addiction (IA) reported moderate to high prevalence rates of IA and comorbid psychiatric symptoms in users of social networking sites (SNS) and online role-playing games. The aim of this study was to characterize adult users of an Internet multiplayer strategy game within a SNS. Therefore, we conducted an exploratory study using(More)
Continuous improvements in the diagnosis and treatment of cancer lead to improved cure rates and longer survival. However, in many patients, the disease becomes chronic. In this context, the patients' quality of life (QOL) becomes a crucial issue. After an introduction about QOL, results from different areas of cancer treatment are presented considering(More)