Anna Sieradzka

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Thyroid metastases account for approximately 1.4-3% of all malignancies of the thyroid gland. Thyroid metastases are most common in: clarocellular carcinoma of the kidney, lung cancer, breast cancer, malignant melanoma and cancers of gastrointestinal tract. A rare situation is when thyroid metastasis is diagnosed before detecting primary malignant focus and(More)
PREOPERATIVE DIAGNOSTIC INVESTIGATIONS OF NODULAR GOITER ARE BASED ON TWO MAIN EXAMINATIONS: ultrasonography of the thyroid gland and ultrasound-guided fine-needle aspiration biopsy. So far, FNAB has been the best method for the differentiation of nodules, but in some cases it fails to produce a conclusive diagnosis. Some of the biopsies do not provide(More)
INTRODUCTION Standard pre-operative diagnosis of nodular goitre is not always conclusive. The decision about nodular goitre surgery is increasingly based on molecular methods. The aim of the study was to determine BRAF T1799A mutation and KRas proto-oncogene mutation, and the analysis of RASSF1A promoter methylation level in cytological material obtained(More)
Introduction Follicular thyroid cancer, similar to follicular adenoma, usually takes the form of a round, encapsulated tumour. Cytological examination does not allow a firm diagnosis of follicular thyroid cancer to be made. Follicular thyroid cancer can be diagnosed by histopathological examination only after demonstrating the infiltration of the capsule by(More)
Introduction The incidence of metastatic thyroid tumours range from 2 to 3% of all thyroid cancer cases. Histological and immunohistochemical examination plays a decisive role in metastasis recognition. Metastases to the thyroid gland are rarely identified in cytological diagnostics. Patients who were postoperatively recognized with metastasis to the(More)
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