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Von Willebrand disease (VWD) is the most common inherited bleeding disorder caused by quantitative or qualitative defects of the von Willebrand factor (VWF). VWD is classified into three types--type(More)
Forty per cent of haemophilia A (HA) patients have missense mutations in the F8 gene. Yet, all patients with identical mutations are not at the same risk of developing factor VIII (FVIII) inhibitors.(More)
UNLABELLED BACKGROUND Approximately 25% of severe hemophilia A (HA) patients develop antibodies to factor VIII protein. PATIENTS In the present case-controlled cohort study, 260 severely(More)