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The aim of this study is to evaluate the empathic ability and its functional brain correlates in post-traumatic stress disorder subjects (PTSD). Seven PTSD subjects and ten healthy controls, all present in the L'Aquila area during the earthquake of the April 2009, underwent fMRI during which they performed a modified version of the Multifaceted Empathy(More)
OBJECTIVE The primary aim of our study was to evaluate if a group of medication-overuse headache (MOH) patients present dysfunctions in the mesocorticolimbic dopamine circuit. The secondary aim was to disentangle the role of the medication overuse and of the acute/chronic headache in determining these alterations and to investigate their persistence. (More)
OBJECTIVE To identify a possible functional imaging biomarker sensitive to the earliest neural changes in premanifest Huntington disease (preHD), allowing early therapeutic approaches aimed at preventing or delaying clinical onset. METHODS Sixteen preHD and 18 healthy participants were submitted to anatomical acquisitions and functional MRI (fMRI)(More)
Previous studies have demonstrated the possibility of using functional MRI to control a robot arm through a brain-machine interface by directly coupling haemodynamic activity in the sensory-motor cortex to the position of two axes. Here, we extend this work by implementing interaction at a more abstract level, whereby imagined actions deliver structured(More)
The “default mode”, or baseline of brain function is a topic of great interest in schizophrenia research. Recent neuroimaging studies report that the symptoms of chronic schizophrenia subjects are associated with temporal frequency alterations as well as with the disruption of local spatial patterns in the default mode network (DMN). Previous studies both(More)
An outstanding issue in graph-theoretical studies of brain functional connectivity is the lack of formal criteria for choosing parcellation granularity and correlation threshold. Here, we propose detectability of scale-freeness as a benchmark to evaluate time-series extraction settings. Scale-freeness, i.e., power-law distribution of node connections, is a(More)
In the last several years, neuroimaging studies have greatly increased our knowledge of cluster headache (CH) pathophysiology (1). The main neuroimaging techniques used to investigate functional and structural changes in CH include positron-emission tomography (PET) (2,3), functional magnetic resonance imaging (fMRI) (4–6), structural magnetic resonance(More)
Differential diagnosis between Vegetative State and Minimally Conscious State is a challenging task that requires specific assessment scales, involvement of expert neuropsychologists or physicians and use of tailored stimuli for eliciting behavioural responses. Although misdiagnosis rate as high as 40% has been reported, no clear guidelines are available in(More)
The purpose of this study was to investigate whether artificial neural networks (ANN) are able to decode participants' conscious experience perception from brain activity alone, using complex and ecological stimuli. To reach the aim we conducted pattern recognition data analysis on fMRI data acquired during the execution of a binocular visual rivalry(More)
This study investigated whether functional transcranial Doppler ultrasound (fTCD) is a suitable tool for studying hemispheric lateralization of language in patients with pre-perinatal left hemisphere (LH) lesions and right hemiparesis. Eighteen left-hemisphere-damaged children and young adults and 18 healthy controls were assessed by fTCD and fMRI to(More)