Anna Mansour

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Formation of the hematopoietic stem cell (HSC) niche in bone marrow (BM) is tightly associated with endochondral ossification, but little is known about the mechanisms involved. We used the oc/oc mouse, a mouse model with impaired endochondral ossification caused by a loss of osteoclast (OCL) activity, to investigate the role of osteoblasts (OBLs) and OCLs(More)
Children and adolescents are at an age where they are beginning to gain autonomy over choosing the foods they eat, yet may not have adequate support or information to make informed choices. This paper describes the design of a heuristic-based health game called <i>MunchCrunch</i> to help this age group learn more about healthy and unhealthy foods to develop(More)
In many cell types, growth factor removal induces the release of cytochrome-c from mitochondria that leads to activation of caspase-9 in the apoptosome complex. Here, we show that sustained stimulation of the Raf-1/MAPK1,3 pathway prevents caspase-9 activation induced by serum depletion in CCL39/ΔRaf-1:ER fibroblasts. The protective effect mediated by Raf-1(More)
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