Anna Malawista

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The TAM receptors (Tyro3, Axl, and Mer) are a family of homologous receptor-tyrosine kinases that inhibit Toll-like receptor signaling to regulate downstream pathways and restore homeostasis. TAM triple mutant mice (Tyro3(-/-), Axl(-/-), Mer(-/-)) have elevated levels of pro-inflammatory cytokines and are prone to developing lymphoproliferative disorders(More)
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