Anna-Lena Dittrich

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BACKGROUND Longstanding ulcerative colitis (UC) bears a high risk for development of UC-associated colorectal carcinoma (UCC). The inflammatory microenvironment influences microRNA expression, which in turn deregulates target gene expression. microRNA-26b (miR-26b) was shown to be instrumental in normal tissue growth and differentiation. Thus, we aimed to(More)
40 acute schizophrenic in-patients were examined using a rating scale (AMP-system) and a self-report questionnaire (APZ) immediately after their admission and on average 7 weeks later. The aim of the study was to clarify the usefulness of self-report questionnaires in schizophrenic patients. There were four groups of subjects: 1. Patients, who filled in the(More)
The study compares altered states of consciousness induced by the hallucinogens (--)delta9-trans-Tetrahydrocannabinol (delta9-THC) and N,N-Dimethyltryptamine (DMT) using two placebo control groups. A total of 24 subjects received 250 mug delta9-THC p.o./kg body weight and 26 subjects were treated with 250 mug DMT i.m./kg. Placebo was given to 24 subjects.(More)
A study of total sleep deprivation for one night was performed on 12 patients with endogenic depression and 10 with neurotic depression, as well as a control group of 10 normals. The study was designed to answer the following questions: 1. Are the correlations between self-ratings and clinical assessments of sleep deprivation effects satisfactory? 2. Are(More)
In a double-blind study on 36 volunteers the effects of 250 mug/kg (--)delta-9-trans-tetrahydrocannabinol p.o. on objective and performance tests measuring psychoticism according to Eysenck were assessed. The hypothesis was tested that subjects treated with delta-9-THC differ from those receiving placebo in the same way as endogenous psychotics differ from(More)
In a controlled study on 38 volunteers the effects of 250 mcg/kg N,N-Dimethyltryptamine (DMT) i.m. were assessed. 26 subjects received DMT and 12 placebo. The altered states of consciousness and the somatic changes were measured by several questionnaires administered after the experiment. In spite of the low dose as compared to previous studies significant(More)
In a controlled study on 38 volunteers the effects of 250 micrograms/kg N,N-dimethyltryptamine (DMT) i.m. on objective and performance tests measuring psychoticism according to Eysenck were assessed. The hypothesis was tested that subjects treated with DMT (N = 26) differ from those receiving placebo (N = 12) in the same way as endogenous psychotics differ(More)
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