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1alpha,25-Dihydroxyvitamin D3 [1,25(OH)2D3] regulates calcium homeostasis and controls cellular differentiation and proliferation. The vitamin D receptor (VDR) is a ligand-regulated transcription factor that recognizes cognate vitamin D response elements (VDREs) formed by direct or everted repeats of PuG(G/T)TCA motifs separated by 3 or 6 bp (DR3 or ER6).(More)
We propose a hierarchical Bayesian model for analyzing multi-site experimental fMRI studies. Our method takes the hierarchical structure of the data (subjects are nested within sites, and there are multiple observations per subject) into account and allows for modeling between-site variation. Using posterior predictive model checking and model selection(More)
  • Melody Lim, Anthony Hou, Natalie Congdon, Janine Chua, Fred Park, Ernie Esser +1 other
  • 2013
Hepatocyte Growth Factor (HGF) has been shown to be increased in the tumor microenvironment due to increased secretion by cancer-associated stromal cells. Qualitatively , high extracellular HGF has been correlated with increased growth and dispersiveness of a tumor. In this study, we develop quantitative methods to measure HGF-induced tumor growth and(More)
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