Precision-cut lung slices (PCLS) allow comparison of the airway responses of different species under identical experimental conditions. The aim of this study was to establish and characterise PCLS… (More)
We previously reported the molecular cloning of a mouse guanosine-nucleotide-binding-protein-coupled receptor similar to the thrombin receptor. Since the physiological agonist was unknown, the… (More)
A member of the Theta class of human glutathione transferases (GST T1-1) was found to display the greatest catalytic activity towards the cytostatic drug 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)… (More)
We have reported the cloning from mouse genomic DNA of a fragment encoding a G-protein-coupled receptor related to the receptor for the blood clotting enzyme thrombin. Like the thrombin receptor this… (More)
Studies of protein structure provide information about principles of protein design that have come into play in natural evolution. This information can be exploited in the redesign of enzymes for… (More)
A large literature documents that autocratic regimes have not, on average, outperformed democratic regimes, although they do display greater variance in economic performance. At the same time, no… (More)
Bounding a scientific discipline is a way of regulating its cognitive direction as well as its relations to neighboring disciplines and extra-academic authorities. In this process of identity making,… (More)
N-Nb(2)O(5) [C2/m (No. 12), a = 28.51, b = 3.830 and c = 17.48 A, and beta = 124.8 degrees ] has been investigated by means of selected-area electron diffraction (SAED) and high-resolution… (More)