Michele Solimena3
Anke Sönmez2
Bernard Mulligan2
Hassan Mziaut2
3Michele Solimena
2Anke Sönmez
2Bernard Mulligan
2Hassan Mziaut
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The existing view is that cortical oligodendrocytes (OLs) in rodents are born from the cortical subventricular zone (SVZ) after birth, but recent data suggest that many forebrain oligodendrocyte progenitor cells (OPCs) are specified much earlier (between E9.5 and E13.5 in the mouse) in the ventricular zone of the ventral forebrain under the control of sonic(More)
  • Rayna I. Kraeva, Dragomir B. Krastev, Assen Roguev, Anna Ivanova, Marina N. Nedelcheva-Veleva, Stoyno S. Stoynov
  • 2007
Nucleic acids, due to their structural and chemical properties, can form double-stranded secondary structures that assist the transfer of genetic information and can modulate gene expression. However, the nucleotide sequence alone is insufficient in explaining phenomena like intron-exon recognition during RNA processing. This raises the question whether(More)
Insulin secretion is key for glucose homeostasis. Insulin secretory granules (SGs) exist in different functional pools, with young SGs being more mobile and preferentially secreted. However, the principles governing the mobility of age-distinct SGs remain undefined. Using the time-reporter insulin-SNAP to track age-distinct SGs we now show that their(More)
Myelin formation and maintenance depends on the establishment of two structurally and biochemically discernible domains: (a)compact myelin, that is multilamellar stacks of plasma membrane sheets; and (b) cytoplasmic channels that border the compact myelin domains, attach them to the cell body and anchor the myelin sheath to the axonal membrane. To identify(More)
BACKGROUND Thrombopoietin (Thpo) and its receptor (Mpl), which regulate megakaryopoiesis, are expressed in the central nervous system (CNS), where Thpo is thought to exert pro-apoptotic effects on newly generated neurons. Mpl expression has been analysed in brain tissue on transcript level and in cultured primary rat neurons and astrocytes on protein level.(More)
OBJECTIVE Insulin release from pancreatic islet β cells should be tightly controlled to avoid hypoglycemia and insulin resistance. The cortical actin cytoskeleton is a gate for regulated exocytosis of insulin secretory granules (SGs) by restricting their mobility and access to the plasma membrane. Prior studies suggest that SGs interact with F-actin through(More)
While hepatitis E is a growing health concern in Europe, epidemiological data on hepatitis E virus (HEV) in Estonia are scarce. Along with imported HEV infections, autochthonous cases are reported from European countries. Both domestic and wild animals can be a source of human cases of this zoonosis. Here, we investigated the presence of anti-HEV antibodies(More)
In situ measurements consisting of stomatal conductance, air temperature, vapor pressure deficit and the spectral reflectance in the shortwave infrared (SWIR) regions of thirty " Conference " pear trees (Pyrus communis L.) were repeatedly measured for eighty-six days. The SWIR was segmented into eight regions between 1550 and 2365 nm, where distances ranged(More)
OBJECTIVE To examine whether the minimum as well as the maximum voice intensity (i.e. sound pressure level, SPL) curves of a voice range profile (VRP) are required when discovering different voice groups based on a clustering analysis. In this approach, no a priori labeling of voice types is used. PATIENTS AND METHODS VRPs of 194 (84 male and 110 female)(More)