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Enzymatic activation of irinotecan (CPT-11) is due to carboxylesterase (CES), and its pharmacological behavior is influenced by drug resistance-related proteins. We previously reported that the(More)
To the Editor The 5-fluorouracil (5-FU)–leucovorin–irinotecan– oxaliplatin (FOLFIRINOX) regimen is increasingly being used for the first-line treatment of metastatic pancreatic cancer showing a(More)