Anna Coble

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Isolated frog skin was irradiated with I-MHz noncavitating focused ultrasound, intensity range 1-100 W/cm 2, in an adaptation of the 0ssing ch•imbcr providing continuous perfusion of the specimen. The electrical parameters of the skin, viz., the membrane potential 0alP) and the short circuit current (SCC), were monitored continuously before, during, and(More)
Electroporation of biological cell membranes is a phenomena that occurs almost universally at a transmembrane potential of approximately 1000 mV. Theories of pore formation have been proposed based on electrocompression (Crowley 1972, Malderelli and Steebe 1992 ), local membrane defects ( Abidor and Chizdhmazdev 1979, Weaver and Mintzer 1981, Sugar 1981),(More)
The electropermeabilization of biological cell membranes by the application of an external field occurs whenever an applied field exceeds a threshold value. For fields above this threshold value but less than another critical value, the pores formed in the membrane are transient or reversible. Several mechanisms have been proposed for the formation of these(More)
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