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Eating disorders (EDs) are complex psychiatric diseases that include anorexia nervosa and bulimia nervosa, and have higher than 50% heritability. Previous studies have found association of BDNF and NTRK2 to ED, while animal models suggest that other neurotrophin genes might also be involved in eating behavior. We have performed a family-based association(More)
BACKGROUND The study of the human DNA methylome has gained particular interest in the last few years. Researchers can nowadays investigate the potential role of DNA methylation in common disorders by taking advantage of new high-throughput technologies. Among these, Illumina Infinium assays can interrogate the methylation levels of hundreds of thousands of(More)
Autism is a developmental disorder which presents disability in communication and socialisation and a lack of imagination. To promote creativity, exploration and enjoyment in low functioning autistic children that have no verbal communication, we propose MEDIATE, an interactive environment that generates real time visual, aural and vibrotactile stimuli.(More)
This paper identifies and contextualizes the limitations and problems found in interactive installations that require a massive flux of users. It then presents a set of solutions for these practical problems and shows how they have been applied to a real life installation with exceptionally good results. The application is an interactive water installation(More)
The design of an interactive system for children with severe autism and no verbal communication is one of the most challenging areas a designer of interactive systems can approach; mainly because of the exceptional type of user involved. In fact, this user cannot be typified because autism is not a unique disability but rather a spectrum of disabilities.(More)
In order to comply with copyright obligations regarding electronic information dissemination of IEEE-copyrighted material the following copyright notice has to be prominently displayed on the initial screen of the authors and/or their companies servers displaying this material. In this case it is a specific document, that is IEEE-copyrighted, and therefore(More)
Radio Frequency Identification (RFID) offers an extraordinary opportunity to enhance the shopping experience of customers in a retail store. There are two types of possible enhancements: increasing the efficiency of traditional processes, or offering new use cases at the store. RFID offers a great opportunity in both cases. RFID can be used to improve the(More)
Social Networks, as the main axis of Web 2.0, are creating a number of interesting challenges to the research and standardisation communities. In this paper, we analyse the current and future use of access control policies in Social Networks. Subsequently, two main issues are addressed: the interoperability amongst systems using different policy languages(More)
On starting to think about interaction design for low-functioning persons in the autistic spectrum (PAS), especially children, one finds a number of questions that are difficult to answer: Can we typify the PAS user? Can we engage the user in interactive communication without generating frustrating or obsessive situations? What sort of visual stimuli can we(More)