Anna A Bouman

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Aluminium in human tissues has been determined by flameless atomic absorption spectroscopy (AAS). Tissues were dried at 110 degrees C and digested with concentrated nitric acid at 50 degrees C overnight. After dilution with distilled water the samples were measured. The aluminium levels of the controls (healthy individuals who died as a result of an(More)
Serum bone alkaline phosphatase (ALP; EC 3.1.3.1) was measured with a wheat germ agglutinin (WGA) precipitation assay and with a new IRMA in a group of healthy elderly women. Both assays were correlated with serum total ALP activity and with osteocalcin. The two bone ALP assays have comparable within- and between-run imprecisions (WGA assay within-run CVs(More)
BACKGROUND Test 1 is a recently introduced technique claiming to determine Erythrocyte Sedimentation Rate (ESR) in 20 s. In contrast to the original Westergren procedure this new technique uses undiluted blood and operates at 37 degrees C. It is hypothesized that Test 1 is in fact an erythrocyte aggregometer and does not measure any sedimentation. METHODS(More)
OBJECTIVES Comparison of the effect of corticosteroid therapy on the diagnostic performance of cystatin C (Cys) and beta-trace protein (bTP), two endogenous markers of GFR. DESIGN AND METHODS Out of a total of 193 pediatric inulin clearance studies, a random sample of 85 steroid-free studies served to establish GFR prediction equations (eGFR), which were(More)
Peak bone mass reaches its peak value at late adolescence and is an important determinant for osteoporosis. Bone growth and bone mass accelerate during puberty. In Amsterdam we started a longitudinal study with 155 healthy pubertal girls to describe this process in detail. The first results of the baseline values of the markers of bone and collagen(More)
In this study we examined whether the effect of continuously combined hormone replacement therapy (HRT) on bone metabolism is influenced by dydrogesterone dose, smoking and initial degree of bone turnover. In a double-blind randomized study, 123 healthy postmenopausal women (mean age 51.7 years; range 30-61 years) received 17 beta-estradiol, 2 mg orally per(More)