Ann Marie Clark

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The intestinal lymphoid follicles and associated structures are specialised antigen sampling and inductive sites of the mucosal immune system. The overlying follicle-associated epithelium (FAE) includes the specialised antigen sampling M cells that are also exploited as a route of pathogen invasion. In this immunohistochemical study we analysed the(More)
In February 2003, a postal survey of 1279 sheep farmers in the Shetland Islands yielded 586 responses (46 per cent response rate). The principal aim of the survey was to gather information on the history and control of scrapie. Overall, 28.5 per cent of the respondents thought they had had a case of scrapie in their flock at some time. There was a slow(More)
We use microsatellite loci to examine genetic structure of the Florida scrub lizard (Sceloporus woodi) and test for the effects of landscape variables at the scale of neighboring patches. We evaluate ecological metrics of connectivity with genetics data, which to our knowledge is the first application of these particular metrics to landscape-level genetics(More)
To address the needs of cancer patients and their caregivers, Microsoft Research and the Fred Hutchinson Cancer Research Center developed HutchWorld, an online community environment, to provide computer-mediated social and informational support. In a controlled clinical study, we deployed HutchWorld to bone marrow transplant patients and their caregivers(More)
A scheme to control and eradicate bovine virus diarrhoea (BVD) was initiated in 1994 in the Shetland Islands by local veterinary surgeons and funded by the Shetland Islands Council and Shetland Enterprise Company. Over a 3-year period every bovine animal on the islands was blood-sampled (heparinised) and laboratory tested using MAb-based ELISAs for BVD(More)
The Virtual World Group (VWG) in Microsoft Research and the Fred Hutchinson Cancer Research Center (the Hutch) are collaborating to develop and study online social support systems for patients at the Hutch. Medical research has shown that social support contributes positively toward psychological and physical well-being. However, in the real world, it is(More)