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Human infants can discriminate the orientation of lines within the first week after birth (Atkinson et al., 1988; Slater et al., 1988) but have immature orientation-selective pattern masking until after 6 months of age (Morrone and Burr, 1986). Here the development of orientation processing is further examined using a visual-evoked potential paradigm and(More)
We used a visual evoked-potential measure to study the development of two components of pattern vision, vernier acuity and grating acuity, in humans from early infancy through adolescence. These two visual functions develop at similar rates and have nearly the same absolute values between 1 month and 6 years of age. After age 6, grating acuity is constant(More)
The ability of 3-month-old human infants to detect the presence of spatial misalignments in single-bar stimuli was investigated in a series of spatiotemporal stimulus manipulations. Both discrete and sinusoidal positional offsets, either stationary or temporally modulated, were presented using the forced-choice preferential looking technique. When discrete(More)
PURPOSE To compare the developmental sequences of two basic measures of pattern vision, Vernier acuity and grating acuity, using steady state visual-evoked potentials (VEPs) and an analysis designed to isolate pattern-specific responses from those due to motion in the Vernier stimulus. METHODS The authors recorded VEPs from 57 healthy full-term infants(More)
Cortical visual impairment (CVI) is the leading cause of bilateral visual impairment in children in Western countries 1–3. This finding reflects better methods for identifying visual impairment due to CNS injury and also advances in perinatal care, which have increased the survival rate of children with neurological morbidity. This review will describe(More)
Cortical visual impairment (CVI) refers to bilateral impairment of vision that is usually due to damage occurring perinatally in the visual cortex and/or optic radiations. The most common cause of this damage is hypoxia, and other causes include encephalitis, meningitis, and trauma. Relatively little research has been done to quantify visual abilities in(More)
  • P Hogan, P Schofield, Chapman, L M Papaioannou, V E Tbx, Wilkinson +36 others
  • 1998
697 Cells mutant for fibroblast growth factor receptor-1, when analysed in chimaeras, fail to ingress normally through the primitive streak and differentiate as ectopic neural-tube extensions of the endogenous neural tube 21,22. Although fibroblast growth factors (FGFs) and some T-box proteins other than Tbx6 may function in the same signalling pathway 23 ,(More)
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