Ann Griffith

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A brief survey of research in the development of autonomy in wheelchairs is presented and AAI's R&D to build a series of intelligent autonomous wheelchairs is discussed. A standardized autonomy management system that can be installed on readily available power chairs which have been well-engineered over the years has been developed and tested. A(More)
The thymus is composed of multiple stromal elements comprising specialized stromal microenvironments responsible for the development of self-tolerant and self-restricted T cells. Here, we investigated the ontogeny and maturation of the thymic vasculature. We show that endothelial cells initially enter the thymus at E13.5, with PDGFR-β(+) mesenchymal cells(More)
T lymphocytes are essential mediators of immunity that are produced by the thymus in proportion to its size. The thymus atrophies rapidly with age, resulting in progressive diminution of new T cell production. This decreased output is compensated by duplication of existing T cells, but it results in gradual dominance by memory T cells and decreased ability(More)
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