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Explants of cranial neural crest from neurula-stage Ambystoma mexicanum embryos form cartilage nodules in 10-14 days, when cultured with pharyngeal endoderm. The time course of formation of the nodules, and their appearance, correspond closely to that observed for visceral cartilage in vivo. Endoderm from any area of the sheet surrounding the pharyngeal(More)
The development of the vertebrate face is a dynamic multi-step process which starts with the formation of neural crest cells in the developing brain and their subsequent migration to form, together with mesodermal cells, the facial primordia. Signalling interactions co-ordinate the outgrowth of the facial primordia from buds of undifferentiated mesenchyme(More)
Tooth development in urodele amphibians occurs from a restricted region of anterior cranial neural crest. An in vitro culture system was used to test the odontogenic potential of more caudal regions of neural crest, including an "intermediate region" of neural folds which has never previously been tested for either fate or potential. Explants of different(More)
The abnormalities of haploid medaka embryos were characterized by comparative analysis of histologic sections and expression patterns of some developmental marker genes between haploids and diploids to clarify whether medaka haploids are useful for identifying mutants. During gastrulation, an obvious defect was first observed as a delay of epiboly and(More)
Beginning at mid-neurulation, a wave of somite segmentation passes down the axolotl body axis in a cephalocaudal direction. At 20 degrees C a somite forms every 2.57 hr. Fate-mapping of the presomitic mesoderm indicates that the primordia for the next few somites occupy nearly the same space that they will after segmentation, but that the remaining somites(More)
Based on results of transplantation experiments, it has long been believed that trunk neural crest cells are incapable of chondrogenesis. When pigmented trunk neural crest cells of Ambystoma mexicanum are transplanted to cranial levels of albino (a/a) embryos, the graft cells ultimately produce ectopic fins, but are incapable of following the chondrogenic(More)
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