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BACKGROUND A robust human challenge model for Campylobacter jejuni is an important tool for the evaluation of candidate vaccines. The previously established model conveys a potential risk of Guillain-Barré syndrome attributable to lipooligosaccharide ganglioside mimicry. This work establishes a new C. jejuni human challenge model that uses a strain (CG8421)(More)
BACKGROUND Campylobacter jejuni is a common cause of diarrhea and is associated with serious postinfectious sequelae. Although symptomatic and asymptomatic infections are recognized, protective immunity is not well understood. Previous data suggests that interferon γ (IFN-γ) may be associated with protection. To better define the clinical and immunologic(More)
OBJECTIVE Beginning in 1995, Illinois law permitted targeted-as opposed to universal-blood lead screening in low-risk areas, which were defined by ZIP code characteristics. State guidelines recommended specific lead risk assessment questions to use when targeting screening. This study was designed to evaluate the sensitivity and specificity of Illinois lead(More)
M01ZH09, S. Typhi (Ty2 Delta aroC Delta ssaV) ZH9, is a single oral dose typhoid vaccine with independently attenuating deletions. A phase II randomized, double-blind, placebo-controlled, dose-escalating trial evaluated the safety and immunogenicity of M01ZH09 to 1.7 x 10(10) colony-forming units (CFU). 187 Healthy adults received vaccine or placebo in four(More)
In the mid-1980s, international students enrolled at Ohio University were identified as a high-risk group for tuberculosis (TB), contributing an estimated 30%-50% of all active TB cases in the sparsely populated county where the university is located. While the student health center routinely screened all newly enrolled international students with PPD(More)
In 1987, the Panel on Occupational Safety and Health Statistics issued a report concluding that the existing national surveillance system for occupation injuries might result in substantial underreporting of occupational injuries. In this study, we examined two sources of data on occupational injuries, the National Electronic Injury Surveillance System(More)
  • A R Fingar
  • Journal of American college health : J of ACH
  • 1989
Descriptions of the health problems of our student populations can be valuable in many ways, including facility planning, staff and student education, quality assurance programs, and research. Planning for national programs requires a description of student health practices nationwide. I encourage ACHA or other organizations to support the collection and(More)
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