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OBJECTIVE To explore the use of classical feedback control methods to achieve an improved deep brain stimulation (DBS) algorithm for application to Parkinson's disease (PD). APPROACH A computational model of PD dynamics was employed to develop model-based rational feedback controller design. The restoration of thalamocortical relay capabilities to(More)
Proper rhythm of the heart of a human is of utmost importance for his survival so that there is proper oxygen supply throughout the body for proper functioning of all body parts. However, Ventricular Tachycardia(VT) and Ventricular Fibrillation(VF) are irregular cardiac rhythms that are life threatening and hence their accurate detection is very necessary.(More)
A 73-year-old female treated with clopidogrel for vascular disease presented with sudden onset of back pain, urinary retention and paraplegia. MRI scans demonstrated a thoracolumbar epidural hematoma and the patient underwent emergency laminectomy for evacuation of the hematoma. A possible causal link between clopidogrel and occurrence of the hemorrhage is(More)
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