Ankit Awasthi

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Aging and increased amyloid burden are major risk factors for cognitive diseases such as Alzheimer's disease (AD). Effective therapies for these diseases are lacking. Here, we evaluated mouse models of age-associated memory impairment and amyloid deposition to study transcriptome and cell type-specific epigenome plasticity in the brain and peripheral(More)
Interactions between astrocytes and neurons rely on the release and uptake of glial and neuronal molecules. But whether astrocytic vesicles exist and exocytose in a regulated or constitutive fashion is under debate. The majority of studies have relied on indirect methods or on astrocyte cultures that do not resemble stellate astrocytes found in vivo. Here,(More)
The role of perception in sighted infant motor development is well-established, but what are the processes by which an infant manages to handle the complex high-dimensional visual input? Clearly, the input has to be modeled in terms of low-dimensional codes so that plans may be made in a more abstract space. While a number of computational studies have(More)
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