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Peripheral lymphocytes from individuals who had been thymectomized in adult life for myasthenia gravis (MG) or for other, nonimmunological reasons showed a moderate decrease in proliferative response capacity to several T-cell mitogens as compared to lymphocytes from normal individuals. The decrease of the response to mitogens and allogeneic lymphocytes was(More)
BACKGROUND Training simulators have been used for decades with success; however, a standardized educational strategy for diagnostic EGD is still lacking. OBJECTIVE Development of a training strategy for diagnostic upper endoscopy. STUDY DESIGN Prospective, randomized trial. SETTINGS A total of 28 medical and surgical residents without endoscopic(More)
The quantitative effects of the antidiarrheal drug loperamide (Imodium®) on several parameters of fecal composition and output were assessed in 7 patients with an ileorectal anastomosis and 7 patients with an ileostomy. Loperamide (two 2 mg capsules tid) or placebo were administered double-blind in two randomly assigned successive 7-day periods. Loperamide(More)
BACKGROUND Hemoclip application in GI-hemorrhage has proven to be effective. Clinical experience shows that multiple clips are frequently necessary. In 2005, an easily reloadable clip-applicator was introduced. We evaluated the hemodynamic efficacy of this new device. MATERIAL/METHODS We prospectively compared the new clipping device (Olympus HX 110/610)(More)
OBJECTIVE Peptic ulcers are the leading cause of upper gastrointestinal (GI) bleeding. The aim of this study was the evaluation of the recent clinical practice in drug therapy and endoscopic treatment of ulcer bleedings in Germany and to compare the results with the medical standard. METHODS A structured questionnaire (cross-sectional study) was sent to(More)
Objective: In this double-blind, randomized, placebo-controlled, dose-finding study we assessed the short-term efficacy and safety of increasing dosages of magnesium pyridoxal-5′-phosphate glutamate (MPPG) compared to placebo in patients with familial hypercholesterolaemia (FH). Twenty-three patients of either sex, over the age of 18 years and suffering(More)
The excretion of sulfated steroids was investigated in the urine and feces of six boys aged 9 months to 7 years and 10 months who had recessive X-linked ichthyosis. Profiles of urinary total steroids as well as sulfated steroids were normal. Cholesterol sulfate excretion in the urine was not elevated. In the feces 2–20% of total cholesterol was cholesterol(More)
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