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OBJECTIVE Vasomotor symptoms may increase the risk for cardiovascular diseases through still elusive mechanisms. Increased cortisol release may favor atherosclerosis. In this study, we tested whether vasomotor and psychological symptoms are associated with an increase in cortisol levels. METHODS A cross-sectional investigation on women in early menopause(More)
OBJECTIVES This study aimed to determine the frequency of dysmenorrhea, as identified by different definitions, in a population of young women, and to investigate factors associated with this complaint. MATERIALS AND METHODS A final group of 408 young women completed a self-assessment questionnaire. This was a cross-sectional analytical study. RESULTS(More)
OBJECTIVES Conflicting evidence indicates an increased risk for cardiovascular disease in postmenopausal women suffering from hot flushes. In this study, we tested whether, beyond hot flushes, menopausal symptoms are associated with biochemical and biophysical risk factors for cardiovascular disease. METHODS Retrospective cross-sectional analysis on 951(More)
OBJECTIVE Combined oral contraceptives (COCs) containing ethinyl-estradiol are known to increase blood pressure (BP). We evaluated whether COCs containing estradiol (E2) influence 24-h ambulatory BP and heart rate (HR) in normotensive and normal-weight women. STUDY DESIGN Twenty-four-hour BP and HR were measured every 30 min with an ambulatory BP device(More)
BACKGROUND/AIMS To investigate the independent importance of different types of pelvic pain on quality of life and depressive symptoms. METHODS A cross-sectional study was performed on patients with pelvic pain. A 10-cm visual-analogue scale (VAS) was used to investigate intensity of intermenstrual pelvic pain, dysmenorrhea or deep dyspareunia. The SF-36(More)
OBJECTIVE The progestin dienogest (DNG) given alone effectively reduces pelvic pain of women with endometriosis. It is not clear whether the same occurs when DNG is associated with estradiol (E2). DESIGN Patient preference prospective observational study. SETTING Outpatient centre of university hospital. PATIENTS 40 patients with endometriosis and(More)
PURPOSE The purpose of this study was to evaluate whether folate exerts antioxidant effects in postmenopausal women and whether this effect is related to folate-induced modification of 24-h ambulatory blood pressure (BP). METHODS Double-blind placebo-controlled study performed in 30 apparently healthy postmenopausal women recruited at the outpatient(More)
OBJECTIVE To assess the impact of ultrasound-estimated uterus position on the intensity of pelvic pain. DESIGN Descriptive analytical study. SETTING Tertiary university gynecology unit. POPULATION 181 consecutive patients with pelvic pain. METHODS Each woman underwent physical examination, transvaginal sonography and filled self-administered(More)
OBJECTIVE To evaluate whether climacteric symptoms are related to pelvic organ prolapse (POP) in postmenopausal women. STUDY DESIGN A cross-sectional investigation was performed on 1382 postmenopausal women attending an outpatient service for menopause at a university hospital. MAIN OUTCOME MEASURES Data regarding climacteric symptoms, as captured by(More)
OBJECTIVES To investigate the management of vaginal atrophy (VA) in a population-based study. STUDY DESIGN A sub-study of a cross-sectional multicenter study on 913 postmenopausal women. MAIN OUTCOME MEASURES Management of VA was investigated on the 274 women referring having received a previous diagnosis of VA. RESULTS Women had received, no therapy(More)