Anjana Varadarajan

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Although gene expression has been studied in bacteria for decades, many aspects of the bacterial transcriptome remain poorly understood. Transcript structure, operon linkages, and information on absolute abundance all provide valuable insights into gene function and regulation, but none has ever been determined on a genome-wide scale for any bacterium.(More)
UNLABELLED Here, we report the development of SOCS (short oligonucleotide color space), a program designed for efficient and flexible mapping of Applied Biosystems SOLiD sequence data onto a reference genome. SOCS performs its mapping within the context of 'color space', and it maximizes usable data by allowing a user-specified number of mismatches.(More)
BACKGROUND Bacillus species are spore-forming bacteria that are ubiquitous in the environment and display a range of virulent and avirulent phenotypes. This range is particularly evident in the Bacillus cereus sensu lato group; where closely related strains cause anthrax, food-borne illnesses, and pneumonia, but can also be non-pathogenic. Although much of(More)
The title compounds have been synthesized in good yields by the interaction of 2,3,4-pentanetrione-3-oxime with ethanedithioamide in 1:1, 1:2, and 2:2 mole proportions. The structures of these compounds have been elucidated from its physico-chemical and spectral data and by correlation with well-known products. Preliminary screening of these compounds for(More)
BACKGROUND Although genome-wide transcriptional analysis has been used for many years to study bacterial gene expression, many aspects of the bacterial transcriptome remain undefined. One example is antisense transcription, which has been observed in a number of bacteria, though the function of antisense transcripts, and their distribution across the(More)
Benzeneacetaldehyde-4-hydroxy-alpha-oxo-aldoxime is proposed as a new sensitive and selective reagent for the spectrophotometric determination of cobalt. The reagent reacts with cobalt in the pH range 8.6-9.4 to form a yellow colored 1:3 chelate which is very well extracted in chloroform. Beer's law is obeyed in the concentration range 0.05-1.3 mug ml(-1)(More)
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