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BACKGROUND Tobacco and alcohol induces generation of free radicals and reactive oxygen species, which are responsible for high rate of lipid peroxidation. Malondialdehyde is the most widely used marker of lipid peroxidation. The aim of the study was to estimate serum malondialdehyde level in oral precancer, oral cancer, and normal individuals. MATERIALS(More)
OBJECTIVE Interaction between reactive oxygen species (ROS) and reactive nitrogen species (RNS) is a crucial determinant in the etiology of oral squamous cell carcinoma (OSCC), and antioxidants protect against cellular and molecular damage caused by these. This study aims to evaluate ROS and RNS, together with the total antioxidant capacity (TAC), in serum(More)
Measurement of plasma hemoglobin is useful in variety of clinical conditions. In the present study we have developed a kinetic method to estimate plasma haemoglobin by using o-tolidine. This method is sensitive, rapid, economical, simple and less influenced by interfering substances. It measures plasma haemoglobin in the range of 6 to 400 mg/L (normal range(More)
Catalase is well known antioxidant enzyme which catalyses the dissociation of hydrogen peroxide directly into H(2)O and O(2). Mammalian catalase has been considered as 'a venerable enzyme with new mysteries'. Some aspects of its mechanism of action are mystifying and many of new findings are still unexplained. To fill up the gap we propose the 'Hydroxyl(More)
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