Anita Roberts

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We have developed an in vitro system to examine the influence of adipocytes, a major mammary stromal cell type, on the growth of a murine mammary carcinoma, SP1. Previously, we have shown that 3T3-L1 adipocytes release a mitogenic factor, hepatocyte growth factor, which strongly stimulates proliferation of SP1 cells. We now show that 3T3-L1 pre-adipocytes(More)
BACKGROUND The importance of effective communication between health professionals and patients with cancer is widely recognized. Training programmes aimed at improving key communication skills are becoming increasingly available. PURPOSE To evaluate a communication skills programme delivered to 308 cancer nurses as part of degree/diploma courses. Based on(More)
OBJECTIVE We evaluated the cardiovascular pathologic condition in the recipient twin in twin-to-twin transfusion syndrome and the influence of amnioreduction. STUDY DESIGN Fetal echocardiograms and medical records of 54 pregnancies that were complicated by twin-to-twin transfusion syndrome were reviewed. Recipient twin right and left ventricular wall(More)
Transforming growth factor beta (TGF-13) is angiogenic in vivo. In vitro, endothelial cell proliferation is inhibited by TGF-13. We have correlated this inhibitory effect with an increase in cellular fibronectin synthesis and deposition in a two-dimensional culture system using specific matrix coatings. The inhibitory effect was mimicked by addition of(More)
OBJECTIVE The purpose of this study was to determine the fetal response to submaximal maternal exercise at 22 to 26 weeks in pregnancies with abnormal uterine artery Doppler. STUDY DESIGN This was a prospective comparison of singleton pregnancies with uteroplacental vascular insufficiency (UPVI) (mean uterine pulsatility index [PI] values >1.45 [n = 12])(More)
We investigated the effects of either intravenous (IV) or intrabronchial (IB) treatment with transforming growth factor beta1 (TGF-beta1) during bacterial pneumonia in rats. Immediately following IB Escherichia coli inoculation (T0), animals (n=270) were randomized to receive a single treatment with human recombinant TGF-beta1 either via IV or IB, or via(More)
OBJECTIVES We investigated the impact of selective laser ablation on the cardiovascular pathology of the recipient twin in twin-twin transfusion syndrome. STUDY DESIGN Fetal echocardiograms and medical records were reviewed from 22 pregnancies with severe twin-twin transfusion syndrome where echocardiography was performed before and after laser. RESULTS(More)
Mrs . H e i s m a n c o m e s f o r w a r d wi th t h i s o f f e r in good f a i t h . A n i g g a r d l y r e s p o n s e wou ld s e e m t o c a s t a s l u r u p e n t h e w a y w e a p p r e c i a t e t h e In ter es t s h o w n . T h e t r o p h i e s p l a c e a prem i u m on a l l a r o u n d a b i l i t y a s s t u d e n t a n d a t h l e t e .(More)