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Curcumin, a well-known dietary pigment derived from Curcuma longa, inhibited growth of several types of malignant cells both in vivo and in vitro. However, its mechanism of action still remains unclear. In this study, we have focused primarily on the cytotoxic effects of curcumin on three human tumor cell lines and rat primary hepatocytes. Curcumin induced(More)
Curcumin, an important constituent of turmeric, is known for various biological activities, primarily due to its antioxidant mechanism. The present study focused on the antibacterial activity of curcumin I, a significant component of commercial curcumin, against four genera of bacteria, including those that are Gram-positive (Staphylococcus aureus and(More)
Picrorhiza kurrooa Royle ex Benth. is an endangered plant species of medicinal importance. The medicinal property is attributed to monoterpenoids picroside I and II, which are modulated by temperature. The transcriptome information of this species is limited with the availability of few hundreds of expressed sequence tags (ESTs) in the public databases. In(More)
Nogo-A, a myelin-associated neurite growth inhibitory protein, is implicated in synaptic plasticity. It binds to its receptor namely the Nogo-66 receptor1 (NgR1) and regulates filamentous (F) actin dynamics via small GTPases of the Rho family, RhoA kinase (ROCK), LimK and cofilin. These proteins are associated with the structural plasticity, one of the(More)
— In a rake receiver for coherent binary orthogonal signaling with (1) a delayed received signal configuration, (2) tap weight estimation by adding two matched filtered outputs using the two reference signals, and (3) predetection maximal-ratio combining (MRC), the tap weight estimation errors are not independent of the additive noise in the channel. Hence(More)
—Magnetic cellular automata (MCA) is a variant of quantum-dot-cellular automata (QCA) where neighboring single-domain nanomagnets (also termed as magnetic cell) process and propagate information (logic 1 or logic 0) through mutual interaction. The attractive nature of this framework is that not only room temperature operations are feasible but also(More)
—Consider a Rake receiver for coherent binary an-tipodal signaling with: 1) a delayed received signal configuration; 2) weight estimation by matched filtering using the reference signal along with the decisions of the previous M symbol intervals ; and 3) predetection maximal-ratio combining (MRC). The weight estimation errors here are not independent of the(More)
Grafting is a well-established practice to facilitate asexual propagation in horticultural and agricultural crops. It has become a method for studying molecular aspects of root-to-shoot and/or shoot-to-root signaling events. The objective of this study was to investigate differences in gene expression between the organs of the scion and rootstock of a(More)