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PURPOSE To determine the consequences of expression of a novel connexin50 (CX50) mutant identified in a child with congenital total cataracts. METHODS The GJA8 gene was directly sequenced. Formation of functional channels was assessed by the two-microelectrode voltage-clamp METHOD Connexin protein levels and distribution were assessed by immunoblot(More)
Burkholderia cepacia complex (Bcc) is a complex group of bacteria causing opportunistic infections in immunocompromised and cystic fibrosis (CF) patients. Herein, we report multilocus sequence typing and analysis of the 57 clinical isolates of Bcc collected over the period of seven years (2005-2012) from several hospitals across India. A total of 21(More)
Procalcitonin (PCT) is an innovative and highly specific marker for diagnosis of clinically relevant bacterial infection and sepsis. PCT supports early diagnosis and Clinical decision making. A retrospective study of two classical cases of neutropenic sepsis with elevated PCT levels in cardiac ICU was done. PCT was analyzed using Elecsys Brahms PCT kit.(More)
Pediatric Spontaneous Bile duct perforation is a rare clinical condition with only around 150 cases reported worldwide. Early management gives excellent prognosis but the condition often presents a diagnostic dilemma. Hepato-biliary Technetium-99m-iminodiacetic acid scintiscan is the diagnostic investigation of choice but its availability in third world(More)
We look to you, as medical students nearing graduation, to help transform the quality and value of medical care. Your choice in a residency program will shape your care for patients for years to come and can also present opportunities to lead improvements in health care. Surely, this is one of the most important decisions you will make in your career.(More)
Design is the crucial step while working on any user story during the sprint in an agile culture of software development. A good design can generate good code and moving further in the journey, a good code would have less or minimum bugs by utilizing benefits of various principles of agile like simplicity, pair programming, less is more approach etc. to its(More)
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