Filter Results:
- Full text PDF available (38)
Publication Year
2002
2019
- This year (26)
- Last 5 years (88)
- Last 10 years (127)
Publication Type
Co-author
Journals and Conferences
Learn More
- Muzlifah Haniffa, Amanda Shin, +25 authors Florent Ginhoux
- Immunity
- 2012
Dendritic cell (DC)-mediated cross-presentation of exogenous antigens acquired in the periphery is critical for the initiation of CD8(+) T cell responses. Several DC subsets are described in human… (More)
- Guillaume Hoeffel, Jinmiao Chen, +17 authors Florent Ginhoux
- Immunity
- 2015
Although classified as hematopoietic cells, tissue-resident macrophages (MFs) arise from embryonic precursors that seed the tissues prior to birth to generate a self-renewing population, which is… (More)
- Andreas Schlitzer, Velayutham Sivakamasundari, +12 authors Florent Ginhoux
- Nature Immunology
- 2015
Mouse conventional dendritic cells (cDCs) can be classified into two functionally distinct lineages: the CD8α+ (CD103+) cDC1 lineage, and the CD11b+ cDC2 lineage. cDCs arise from a cascade of bone… (More)
- Graham P Pawelec, Evelyna Derhovanessian, Anis Larbi, Jan Strindhall, Anders Wikby
- Reviews in medical virology
- 2009
'Immunosenescence' is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. Primarily anecdotal evidence implies that… (More)
- Naomi McGovern, Andreas Schlitzer, +22 authors Muzlifah Haniffa
- Immunity
- 2014
Dendritic cells (DCs), monocytes, and macrophages are leukocytes with critical roles in immunity and tolerance. The DC network is evolutionarily conserved; the homologs of human tissue CD141(hi)XCR1⁺… (More)
- Tamás Fülöp, Anis Larbi, Graham P Pawelec
- Front. Immunol.
- 2013
Aging is associated with a dysregulation of the immune response, loosely termed "immunosenescence." Each part of the immune system is influenced to some extent by the aging process. However, adaptive… (More)
- Martin Guilliams, C A Dutertre, +28 authors Florent Ginhoux
- Immunity
- 2016
Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic potential. Multiple DC subsets have been described, and it remains challenging to align them across tissues… (More)
- Tamas Z Fulop, Anis Larbi, +5 authors Gilles Dupuis
- Aging cell
- 2004
It is well known that the immune response decreases during aging, leading to a higher susceptibility to infections, cancers and autoimmune disorders. Most widely studied have been alterations in the… (More)
- Sven Dominik Koch, Anis Larbi, +7 authors Graham P Pawelec
- Annals of the New York Academy of Sciences
- 2007
The human immune system evolved to defend the organism against pathogens, but is clearly less well able to do so in the elderly, resulting in greater morbidity and mortality due to infectious disease… (More)
- Sven Dominik Koch, Anis Larbi, Evelyna Derhovanessian, Dennis Özcelik, Elissaveta J. Naumova, Graham P Pawelec
- Immunity & Ageing
- 2008
T cell-mediated immunity in elderly people is compromised in ways reflected in the composition of the peripheral T cell pool. The advent of polychromatic flow cytometry has made analysis of cell… (More)