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BACKGROUND The mathematical models for patients with diabetes proposed in the literature since the late 1970s are mainly glucocentric (glucose-based); hence, the contribution of free fatty acid (FFA) metabolism in the body and its glucose-insulin interactions have been largely ignored. However, approximately 90% of the muscle energy is derived from FFA(More)
BACKGROUND Regulation of plasma glucose concentration for type 1 diabetic patients is challenging, and exercise is an added complication. From a metabolic prospective, the significant exercise-induced effects are increased glucose uptake rate by the working tissues, increased hepatic glucose release to maintain overall glucose homeostasis, and decreased(More)
UNLABELLED The Marcellus Shale is one of the largest natural gas reserves in the United States; it has recently been the focus of intense drilling and leasing activity. This paper describes an air emissions inventory for the development, production, and processing of natural gas in the Marcellus Shale region for 2009 and 2020. It includes estimates of the(More)
In previous work, we developed an 8-state nonlinear dynamic model of the acute inflammatory response, including activated phagocytic cells, pro- and anti-inflammatory cytokines, and tissue damage, and calibrated it to data on cytokines from endotoxemic rats. In the interest of parsimony, the present work employed parametric sensitivity and local(More)
A mixed meal model was developed to capture the gut absorption of glucose, protein, and free fatty acid (FFA) from a mixed meal into the circulatory system. The output of the meal model served as a disturbance to the extended minimal model, which successfully captured plasma FFA, glucose and insulin concentration dynamics and interactions. A model(More)
This study is primarily focused toward measuring the particle size distribution and chemical analysis of particulate matter that originates from combustion sources typically found in Indian urban homes. Four such sources were selected: cigarette, incense stick, mosquito coil, and dhoop, the latter being actually a thick form of incense stick. Altogether,(More)
Dry deciduous forests of the eastern lateritic part of India are a typical case where forest valuation is yet to be integrated with the non-timber forest products like wild edible mushrooms (WEMs), which have a wide use in subsistence and cash income. A detailed accounting of the production and utilization of WEMs harvested from that region was made to(More)
Arsenic contamination mitigation technologies have been adsorption-based, but the most widely-used and traditionally available adsorbents suffered inherent limitations, including cost infeasibility and problems associated with regeneration and disposal of the spent adsorbent. The present technology is based on indigenously developed activated laterite(More)
The body responds to endotoxins by triggering the acute inflammatory response system to eliminate the threat posed by gram-negative bacteria (endotoxin) and restore health. However, an uncontrolled inflammatory response can lead to tissue damage, organ failure, and ultimately death; this is clinically known as sepsis. Mathematical models of acute(More)