• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
  • Anima Ghosal, Hiroya Satoh, P. E. L. Thomas, Eugene Bush, Diana M. Moore
  • Chemistry, Medicine
  • Drug metabolism and disposition: the biological…
  • 1996 (First Published: 1 September 1996)
  • Midazolam (MDZ) is metabolized in human liver microsomes by the cytochrome P450 (CYP) 3A subfamily to 1'-hydroxy (1'-OH) and 4-hydroxy (4-OH) metabolites. MDZ is metabolized in the rat primarily toContinue Reading
  • Anima Ghosal, Neil Hapangama, +6 authors Shmuel Zbaida
  • Chemistry, Medicine
  • Drug metabolism and disposition: the biological…
  • 2004 (First Published: 1 February 2004)
  • Posaconazole (Noxafil, SCH 56592), an orally available broad-spectrum triazole antifungal, is currently in phase III clinical studies for treating serious opportunistic fungal infections. The majorContinue Reading
  • Anima Ghosal, Neil Hapangama, +4 authors Shmuel Zbaida
  • Chemistry, Medicine
  • Biopharmaceutics & drug disposition
  • 2003 (First Published: 1 December 2003)
  • Cytochrome P450 (CYP) substrates that yield fluorescent metabolites were used for rapid screening of drug metabolism activities of 13 recombinant human cytochromes P450, human liver microsomes andContinue Reading
  • Anima Ghosal, Yuan Yuan, +5 authors Kevin B. Alton
  • Chemistry, Medicine
  • Drug metabolism and disposition: the biological…
  • 2011 (First Published: 1 March 2011)
  • Boceprevir (SCH 503034), a protease inhibitor, is under clinical development for the treatment of human hepatitis C virus infections. In human liver microsomes, formation of oxidative metabolitesContinue Reading
  • Anima Ghosal, Xiaowen Lu, +5 authors Kevin B. Alton
  • Chemistry, Medicine
  • Drug metabolism and disposition: the biological…
  • 2011
  • Vorapaxar (SCH 530348), a potent oral thrombin protease-activated receptor 1 antagonist, is being developed as an antiplatelet agent for patients with established vascular disease. The objective ofContinue Reading
  • Anima Ghosal, Yuan Yuan, +6 authors Shmuel Zbaida
  • Chemistry, Medicine
  • Biopharmaceutics & drug disposition
  • 2004 (First Published: 1 September 2004)
  • Desloratadine is a non-sedating antihistamine recently approved for the treatment of seasonal allergic rhinitis. The major metabolite of desloratadine in human plasma and urine is the glucuronideContinue Reading
  • Michael M. Iba, A Storch, Anima Ghosal, Susan Bennett, Kenneth R. Reuhl, Herbert E. Lowndes
  • Chemistry, Medicine
  • Archives of Toxicology
  • 2003 (First Published: 1 October 2003)
  • We examined the constitutive and inducible levels of microsomal cytochromes P450 1A1 and 1A2 (CYP1A) in rat cerebral cortex and cerebellum at the level of proteins by western blot analysis, and byContinue Reading
  • Peijuan Zhu, Wei Ding, Wei Tong, Anima Ghosal, Kevin B. Alton, Swapan Kumar Chowdhury
  • Chemistry, Medicine
  • Rapid communications in mass spectrometry : RCM
  • 2009 (First Published: 15 June 2009)
  • A retention-time-shift-tolerant background subtraction and noise reduction algorithm (BgS-NoRA) is implemented using the statistical programming language R to remove non-drug-related ion signals fromContinue Reading