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Any business, no matter what physical goods or services it produces, relies on business records. It needs to record details of what it produces in terms of concrete information. Business artifacts are a mechanism to record this information in units that are concrete, identifiable, self-describing, and indivisible. We developed the concept of artifacts, or(More)
A promising approach to managing business operations is based on <i>business artifacts</i>, a.k.a. <i>business entities</i> (<i>with lifecycles</i>). These are key conceptual entities that are central to guiding the operations of a business, and whose content changes as they move through those operations. An artifact type includes both an <i>information(More)
Business process management, workflow, and case management are critical technologies for managing collections of services, including human activities, to support business operations. One way to manage business operations is based on business entities with lifecycles (BEL’s) (a.k.a. business artifacts), i.e., key conceptual entities that are central to(More)
In this paper we use dimensional analysis as a method for solving problems in qualitative physics. We pose and solve some of the qualitative reasoning problems discussed in the literature, in the context of devices such as the pressure regulator and the heat exchanger. Using dimensional analysis, such devices or systems can be reasoned about without(More)
K. Bhattacharya N. S. Caswell S. Kumaran A. Nigam F. Y. Wu For almost a decade, the artifact-centered operational-modeling approach for modeling business operations, also referred to as the ‘‘business artifact method,’’ has been practiced and refined. This approach has been used in a variety of engagements, and each engagement has brought forth innovations(More)
BACKGROUND There is epidemiological evidence that omega-3 polyunsaturated fatty acids (PUFAs) reduce the risk of atrial fibrillation (AF), but clinical data are conflicting. The present study assessed the effects of PUFA on AF in experimental models. METHODS AND RESULTS We studied the effects of oral PUFA supplements in 2 experimental AF paradigms:(More)
BACKGROUND Angiopoietin like-2 (angptl2), a proinflammatory protein, is overexpressed in endothelial cells (ECs) from patients with coronary artery disease (CAD). Whether angptl2 contributes to atherogenesis is unknown. We tested the hypothesis that angptl2 promotes inflammation and leukocyte adhesion onto ECs, thereby accelerating atherogenesis in(More)
BACKGROUND QT dispersion (QTd) is a marker of myocardial electrical instability, and is increased in metabolic syndrome (MetS). Moderate intensity continuous exercise (MICE) training was shown to improve QTd in MetS patients. OBJECTIVES To describe long-term effects of MICE and high-intensity interval exercise training (HIIT) on QTd parameters in MetS. (More)
The aim of this study was to determine the level of agreement between the new Aquatrainer® system and the facemask in the assessment of submaximal and maximal cardiopulmonary responses during exercise performed on ergocycle. Twenty-six physically active healthy subjects (mean age: 41 ± 14 years) performed a submaximal constant work test followed by maximal(More)
OBJECTIVE The aim of this study was to study the impact of a combined long-term lifestyle and high-intensity interval training intervention on body composition, cardiometabolic risk, and exercise tolerance in overweight and obese subjects. DESIGN Sixty-two overweight and obese subjects (53.3 ± 9.7 yrs; mean body mass index, 35.8 ± 5 kg/m(2)) were(More)