Anil Kumar Kela

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Effect of ondansetron (5-HT3-receptor antagonist) was studied on the working memory deficits induced by scopolamine, a muscarinic receptor antagonist in rats using a three-panel runway apparatus. Varying doses of scopolamine (0.1-0.56mg/kg, ip) were administered alone or in combination with ondansetron (0.01-1.0 mg/kg, ip) and memory errors and latency(More)
Ethanol produces alterations in muscular contraction and neuromuscular function both in vitro and in vivo in mammalian and amphibian tissues in dose dependent manner. It is not very well known whether gallamine, a commonly used muscle relaxant produces any interaction with ethanol. Hence in the present study, interactions of ethanol with gallamine are(More)
Alcohol produces contraction of isolated frog rectus abdominis muscle in a dose dependent manner. In the present study interactions of pancuronium, gallamine and succinylcholine with ethanol have been studied. Pancuronium and gallamine behaved in a non-competitive manner with ethanol. The PD'2 values of pancuronium and gallamine were almost similar.(More)
Ethanol, propanol and butanol cause contraction and potentiate the responses of acetylcholine (Ach) on frog's rectus muscle. These actions are minimum with ethanol and maximum with butanol. Various drugs acting at different levels of neuromuscular transmission inhibited the responses of alcohol itself and also its potentiating responses of Ach. The results(More)
The effect of altered fore limb alignment to trunk on mean electrical axis (MEA) and on amplitude of the QRS complex of frontal plane leads was studied in both prone and supine postures in 32 albino rats. It was found that in both postures bilateral extension of fore limbs caused a significant change in MEA to right. Unilateral change in the fore limb(More)
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