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Exposure to particulate matter (PM), a major component of air pollution, contributes to increased morbidity and mortality worldwide. PM induces innate immune responses and contributes to allergic sensitization, although the mechanisms governing this process remain unclear. Lung mucosal uric acid has also been linked to allergic sensitization. The links(More)
Five patients suffering with delusional depression, and who were resistant to tricyclic antidepressants, were successfully treated with lithium carbonate. Delusional depression does not usually respond to tricyclic antidepressants, and ECT has been considered the treatment of choice. Such patients often refuse to acknowledge that they are ill. They,(More)
Application results are described of a new parallel Navier-Stokes solver developed by Nektonics Inc. for NASA. The 3D unsteady code is based on the spectral-element method which combines the geometric exibility of nite-element methods and the high accuracy of spectral methods. The dis-cretization methodology, parallelization technique and performance(More)
News sentiment has been empirically observed to have impact on financial market returns. In this study, we investigate firm-specific news from the Thomson Reuters News Analytics data from 2003 to 2014 and propose an optimal trading strategy based on a sentiment shock score and a sentiment trend score which measure extreme positive and negative sentiment(More)
We introduce a preconditioning technique based on Domain Decomposition and the Fast Diagonalization Method that can be applied to tensor product based discretizations of the steady convection-diffusion and the linearized Navier-Stokes equations. The method is based on iterative substructuring where fast diagonalization is used to efficiently eliminate the(More)
The present work introduces a parallel algorithm for the spectral element method with nonconforming mesh connguration. The solution of the two-dimensional Poisson equation is implemented on the IN-TEL Paragon. Decomposition of the computational domain is performed on an elemental basis, where computational load balance is achieved by mapping a single(More)
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