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The cellular response to DNA damage is mediated by evolutionarily conserved Ser/Thr kinases, phosphorylation of Cdc25 protein phosphatases, binding to 14-3-3 proteins, and exit from the cell cycle.Expand
  • Mary Faris, Barbara Ensoli, +4 authors André E Nel
  • Medicine, Biology
  • AIDS
  • 1996 (First Publication: 1 April 1996)
  • ObjectivesTo determine the integration of signalling pathways associated with two recognized Kaposi's sarcoma (KS) growth factors, oncostatin M (OSM) and basic fibroblast growth factor (bFGF), in theExpand
  • Erin L. Filbert, Anhco Nguyen, Mary A Markiewicz, B J Fowlkes, Yina H Huang, Andrey S Shaw
  • Medicine, Biology
  • European journal of immunology
  • 2010 (First Publication: 1 November 2010)
  • The scaffold protein kinase suppressor of Ras 1 (KSR1) is critical for efficient activation of ERK in a number of cell types. Consistent with this, we observed a defect in ERK activation inExpand