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OBJECTIVES To determine the proportion and type of mutations in Mycobacterium tuberculosis isolates resistant to streptomycin, and their relationship with the level of resistance and with the epidemiological molecular pattern of the isolates. METHODS Sixty-nine streptomycin-resistant isolates from a M. tuberculosis strain collection (1995-2005) from(More)
Tuberculosis (TB) is still a serious public health issue, even in large cities in developed countries. Control of this old disease is based on complicated programs that require completion of long treatments and contact tracing. In an accompanying research article published in BMC Public Health, Bothamley and colleagues found that areas with a ratio lower(More)
Tuberculosis (TB) continues to cause millions of new cases and deaths worldwide every year. The World Health Organization (WHO) has recently estimated that in 2007 9,273,000 cases (incidence 139/100,000 inhabitants) and 1,772,000 deaths were attributed to TB and, in the previous year, the absolute figure was slightly lower (9,240,000 cases) and the(More)
BACKGROUND Mortality among patients who complete tuberculosis (TB) treatment is still high among vulnerable populations. The objective of the study was to identify the probability of death and its predictive factors in a cohort of successfully treated TB patients. METHODS A population-based retrospective longitudinal study was performed in Barcelona,(More)
BACKGROUND Objectives: To determine whether the incidence of tuberculosis with pregnancy is more common than would be expected from the crude birth rate; to see whether there is significant delay in the diagnosis of tuberculosis during pregnancy. METHOD Design: A cross-sectional survey. SETTING 13 tuberculosis clinics within different European countries(More)
OBJECTIVE To study the prevalence of latent tuberculosis infection (LTBI) and the predictive factors amongst immigrants entering prison. METHODS prospective study conducted in May and June of 2009. The tuberculin skin test (TST) was performed, with induration of ≥ 10 mm being regarded as positive. Variables collected were: age, origin, number of(More)
Objective: To study the agreement of Tuberculin Skin Tests (TST) and Interferon Gamma Release Assays (IGRA) when screening tuberculosis infection amongst inmates recently admitted to prison. Materials and Methods: Prospective study conducted in a prison during the months of May and June 2009. Inmates without a TB history, with previous TST negatives or(More)
BACKGROUND Immigration can affect the evolution of TB as an AIDS-defining disease (AIDS-TB). METHODS The Barcelona AIDS register for 1994-2005 was analyzed, and the global characteristics of AIDS-TB and AIDS-non-TB cases were compared. The Mantel-Haenszel test was used in the trend analysis, and logistic regression was used in the multivariate analysis.(More)
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