Angeles C. Tecalco-Cruz

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Estrogen receptor α (ERα) mediates the effects of 17β-estradiol (E2) in normal mammary gland, and it is a key participant in breast cancer tumor development. ERα transactivation activity is mediated(More)
Background: Human skil gene encodes for SnoN, a negative regulator of TGF-β/Smad pathway. Results: We provide a molecular mechanism of transcriptional regulation of the skil gene expression by(More)
Tristetraprolin (TTP) is a 34-kDa, zinc finger-containing factor that in mammalian cells acts as a tumor suppressor protein through two different mechanisms. In the cytoplasm TTP promotes the decay(More)
The transforming growth factor-β (TGF-β) family plays major pleiotropic roles by regulating many physiological processes in development and tissue homeostasis. The TGF-β signaling pathway outcome(More)