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PSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and secreted proteins present in several Leishmania (L.) species. PSA is recognized by human Th1 cells and provides a high degree of protection in vaccinated mice. We evaluated humoral and cellular immune responses induced by a L. amazonensis PSA protein (LaPSA-38S) produced in a L.(More)
Future therapy of spinal cord trauma is based on the careful analysis of pathophysiological phenomena secondary to the initial lesion. The toxicity of excitatory amino-acids, which is an early phenomenon, can be treated by specific antagonists. Axonal regrowth, which spontaneously occurs within days after the trauma must be supported by trophic factors on(More)
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