Angela K Lange

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OBJECTIVE The aim of this cross-sectional study is to investigate the relationship between knee adduction moment and knee adduction angular impulse and meniscus, cartilage and bone morphology in women with knee osteoarthritis (OA). METHOD Forty-five women aged >40 years with OA in at least one knee, according to American College of Rheumatology clinical(More)
Lower limb dynamic alignment represents the limb position during functional loading conditions and obtains valuable information throughout the gait cycle rather than a single instant in time. This study aims to determine whether dynamic alignment is altered in medial knee osteoarthritis (OA) and how dynamic alignment is related to knee adduction moment(More)
OBJECTIVE To assess the effectiveness of isolated resistance training on arthritis symptoms, physical performance, and psychological function in people with knee osteoarthritis. METHODS A comprehensive systematic database search for randomized controlled trials was performed. Two reviewers independently assessed studies for potential inclusion. Study(More)
BACKGROUND Osteoarthritis is a common musculo-skeletal problem accompanied with muscle weakness. Muscle weakness may be readily improved by resistance training. Greater muscle strength has been associated with a lower knee joint loading rate. METHODS We conducted a single-blind randomized controlled trial of 54 female patients with osteoarthritis in at(More)
We have now employed induction chemotherapy in almost 200 women with locally advanced breast carcinoma. Significant tumor regression has been noted in a majority of patients, 85%, permitting definitive local treatment with greater success than heretofore expected. Breast conservation has been offered to a larger proportion of these women as we have gained(More)
OBJECTIVE Meniscus tears are often presumed to be associated with a traumatic event, but they can also occur as a result of the cartilage degeneration process in osteoarthritis (OA). The aim of this paper is to describe the prevalence and clinical correlates of degenerative meniscus tears in women with knee OA. METHOD The subjects were women screened for(More)
BACKGROUND we hypothesised that high intensity progressive resistance training would improve lower limb dynamic alignment and function (lower knee adduction moment, increased muscle strength, and fewer knee osteoarthritis symptoms). METHODS women (n=54) with osteoarthritis in at least one knee were randomised into a 6-month resistance training or a(More)
BACKGROUND This article provides the rationale and methodology, of the first randomised controlled trial to our knowledge designed to assess the efficacy of progressive resistance training on cartilage morphology in women with knee osteoarthritis.Development and progression of osteoarthritis is multifactorial, with obesity, quadriceps weakness, joint(More)
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