Angela Hagendorff

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PURPOSE To determine whether cerebral infarctions classified as embolic or hemodynamic by their appearance on CT scans reflect distinct pathophysiologic entities. METHODS Cerebral infarctions were retrospectively classified into two groups according to their morphologic appearance on CT scans: territorial infarctions and watershed, or terminal supply(More)
Combined alteration of the pyruvate dehydrogenase complex and respiratory chain function is described in a 21 year-old male patient with overlapping MELAS (mitochondrial encephalomyopathy, lactic acidosis, and 'stroke-like' episodes) and Kearns-Sayre syndrome. Progressive external ophthalmoplegia, pigmentary retinopathy and right bundle branch block were(More)
Disorders of the mitochondrial energy metabolism are clinically and genetically heterogeneous. An increasingly recognized subgroup is caused by defective mitochondrial iron-sulfur (Fe-S) cluster biosynthesis, with defects in 13 genes being linked to human disease to date. Mutations in three of them, NFU1, BOLA3, and IBA57, affect the assembly of(More)
The present experiments were designed to compare the behavior of cerebral blood flow (CBF) during acute moderate and severe hypotensive episodes induced by either ventricular tachycardias (VT) or by hemorrhage. Using the microsphere method CBF was determined in 20 Sprague-Dawley rats during sinus rhythm (Group A), in 28 animals during high-rate VT (Group B)(More)
  • Originalarbeiten Breil, Krep H, Heister U, Bartsch A Bender, R Schaefers, Hoeft A +19 others
  • 2013
Randomised study of hyperonic saline infusion during resuscitation from out-of-hospital cardiac arrest. A Hoeft. Out-of-hospital cardiopulmonary resuscitation with the AutoPulse system: A prospective observational study with a new load-distributing band chest compression device. Effects of hypertonic versus isotonic infusion therapy on regional cerebral(More)
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