Angela Giacco

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BACKGROUND AND AIM The intake of wholemeal foods is consistently associated with reduced risk of type 2 diabetes and cardiovascular diseases in epidemiological studies, although the mechanisms of this association are unclear. Here we aim to compare in healthy subjects the metabolic effects of a diet rich in wholemeal wheat foods versus one based on the same(More)
It is commonly believed that high-carbohydrate (CHO) diets improve peripheral insulin sensitivity; however, this concept is based on anecdotal evidence. Furthermore, it has been demonstrated that in non-insulin-dependent diabetic patients treated with insulin, a high-monounsaturated-fat (MUFA) diet is more effective than a high-complex-CHO diet in reducing(More)
OBJECTIVE To evaluate in type 1 diabetic patients 1) the long-term feasibility of a high-fiber (HF) diet composed exclusively of natural foodstuffs and 2) the efficacy of this diet in relation to blood glucose control and incidence of hypoglycemic episodes. RESEARCH DESIGN AND METHODS The study was randomized with parallel groups. Participants were part(More)
To evaluate the effects of a fibre-rich diet on blood glucose and serum lipoproteins, eight diabetic patients, four on insulin and four on oral hypoglycaemic drugs, were put on three different diets, a different one for each consecutive 10-day period: diet A (carbohydrate 53%, fibre 16 g), diet B (carbohydrate 53%, fibre 54 g), and diet C (carbohydrate 42%,(More)
Dietary polyphenols and long chain n-3 polyunsaturated fatty acids (LCn3) are associated with lower cardiovascular risk. This may relate to their influence on glucose metabolism and diabetes risk. We evaluated the effects of diets naturally rich in polyphenols and/or LCn3 of marine origin on glucose metabolism in people at high cardiometabolic risk.(More)
OBJECTIVE To evaluate a new computerized method for recording 7-day food intake. RESEARCH DESIGN AND METHODS Randomized crossover trial was conducted with patients recording the amount and type of every food and drink consumed during a week by either a computerized device (Food-meter) or recording the data in a diary. Each method was applied twice.(More)
A controlled trial of the effect of low versus high calcium intake on blood pressure was performed in 15 patients with mild essential hypertension (supine blood pressure after a 1-month run-in period: 145.7 +/- 2.6/97.8 +/- 0.9 mmHg, mean +/- s.e.m.). After a 1-week baseline period on a standard calcium intake (900 mg/day, obtained by giving a 500-mg(More)
OBJECTIVE To determine whether an increase in dietary potassium intake from natural foods reduces the need for antihypertensive medication in patients with essential hypertension. DESIGN Randomized, controlled trial with 1-year follow-up. SETTING Hypertension outpatient clinic of a university hospital. PATIENTS Fifty-four patients with well-controlled(More)
OBJECTIVES To compare the long term metabolic effects of two diets for treating hyperlipidaemia. DESIGN Randomised controlled study: after three weeks of normal (control) diet, subjects were randomly allocated to one of two test diets and followed up for six months. SETTING Lipid clinic of tertiary referral centre in Naples. SUBJECTS 63 subjects with(More)