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The cellular delivery of therapeutic agents and their localization within cells is currently a great challenge in medicinal chemistry. A few cationic peptides have shown a strong propensity to cross… (More)
Biochemical genetic testing and newborn screening are essential laboratory services for the screening, detection, diagnosis, and monitoring of inborn errors of metabolism or inherited metabolic… (More)
The nuclear localization signal sequence (NLS) of the transcription factor NF-kappaB is a cationic peptide with the ability to cross the cytoplasmic membrane and facilitate the delivery of attached… (More)
The site-specific delivery of chemotherapeutic agents to tumor cells has been a longstanding objective in clinical research . The delivery strategies that have been utilized thus far include the… (More)