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Daily acute intermittent hypoxia elicits functional recovery of diaphragm and inspiratory intercostal muscle activity after acute cervical spinal injury

• Angela A Navarrete-Opazo, Stéphane Vinit, Brendan J Dougherty, Gordon S Mitchell
• Experimental Neurology
• 2015

UNLABELLED A major cause of mortality after spinal cord injury is respiratory failure. In normal rats, acute intermittent hypoxia (AIH) induces respiratory motor plasticity, expressed as diaphragm… (More)

Therapeutic potential of intermittent hypoxia: a matter of dose.

• Angela A Navarrete-Opazo, Gordon S Mitchell
• American journal of physiology. Regulatory…
• 2014

Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and triggers a bewildering array of both detrimental and beneficial effects in multiple physiological systems.… (More)

Recruitment and plasticity in diaphragm, intercostal, and abdominal muscles in unanesthetized rats.

• Angela A Navarrete-Opazo, Gordon S Mitchell
• Journal of applied physiology
• 2014

UNLABELLED Although rats are a frequent model for studies of plasticity in respiratory motor control, the relative capacity of rat accessory respiratory muscles to express plasticity is not well… (More)

Adenosine 2A receptor inhibition enhances intermittent hypoxia-induced diaphragm but not intercostal long-term facilitation.

• Angela A Navarrete-Opazo, Stéphane Vinit, Gordon S Mitchell
• Journal of neurotrauma
• 2014

Acute intermittent hypoxia (AIH) elicits diaphragm (Dia) and second external intercostal (T2 EIC) long-term facilitation (LTF) in normal unanesthetized rats. Although AIH-induced phrenic LTF is… (More)

Repetitive Intermittent Hypoxia and Locomotor Training Enhances Walking Function in Incomplete Spinal Cord Injury Subjects: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial.

• Angela A Navarrete-Opazo, Julio J Alcayaga, Oscar Sepúlveda, Enrique Rojas, Carolina Astudillo
• Journal of neurotrauma
• 2017

Incomplete spinal cord injuries (iSCI) leave spared synaptic pathways below the level of injury. Intermittent hypoxia (IH) elicits plasticity in the spinal cord and strengthens spared synaptic… (More)

Enhanced recovery of breathing capacity from combined adenosine 2A receptor inhibition and daily acute intermittent hypoxia after chronic cervical spinal injury

• Angela A Navarrete-Opazo, Brendan J Dougherty, Gordon S Mitchell
• Experimental Neurology
• 2017

Daily acute intermittent hypoxia (dAIH) improves breathing capacity after C2 spinal hemisection (C2HS) in rats. Since C2HS disrupts spinal serotonergic innervation below the injury,… (More)

Intermittent Hypoxia Does not Elicit Memory Impairment in Spinal Cord Injury Patients.

• Angela A Navarrete-Opazo, Julio J Alcayaga, Denisse Testa, Ana Luisa Quinteros
• Archives of clinical neuropsychology : the…
• 2016

There is a critical need for new therapeutic strategies to restore motor function in patients with spinal cord injuries (SCIs), without unwanted effects. Intermittent hypoxia (IH) induces plasticity… (More)

Intermittent Hypoxia and Locomotor Training Enhances Dynamic but Not Standing Balance in Patients With Incomplete Spinal Cord Injury.

• Angela A Navarrete-Opazo, Julio J Alcayaga, Oscar Sepúlveda, Gonzalo Varas
• Archives of physical medicine and rehabilitation
• 2017

OBJECTIVE To test the effect of combined intermittent hypoxia (IH) and body weight-supported treadmill training (BWSTT) on standing and dynamic balance in persons with incomplete spinal cord injury… (More)

Effectiveness of Oral Baclofen in the Treatment of Spasticity in Children and Adolescents With Cerebral Palsy.

• Angela A Navarrete-Opazo, Waleska Gonzalez, Paula Nahuelhual
• Archives of physical medicine and rehabilitation
• 2016

OBJECTIVE To systematically review the effectiveness of oral baclofen versus placebo or other antispastic oral medications in terms of body function, level of activity, and quality of life in… (More)

intermittent hypoxia: systemic blood pressure Invited Review: Physiological consequences of

• Eugene Fletcher, Angela A Navarrete-Opazo, +8 authors Blake Ivers
• 2015

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