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The dominant models for inventory control of repairable items, both in the literature and in practical applications, are based on the assumption of ample repair capacity. This assumption can introduce a serious underestimation of the spare parts requirements in systems with high repair facility utilization, as is typical in industry. In this paper, we(More)
In the past years, it has been shown that kynurenines pathway is a regulator of both the innate and the adaptive immune responses. Particularly, the initial enzyme of this pathway, indoleamine 2,3-dioxygenase (IDO), is implicated in maintaining tolerance during pregnancy, and also can be expressed in tumors to avoid the immune attack. In this chapter, we(More)
The FOXBOX system puts in practice the black box representation of symbolic objects and provides algorithms for performing the symbolic calculus with such representations. Black box objects are stored as functions. For instance: a black box polynomial is a procedure that takes values for the variables as input and evaluates the polynomial at that given(More)
The effects of L-carnitine on the pyruvate dehydrogenase (PDH) complex and carnitine palmitoyl transferase (CPT) were studied in muscle of 16 long-distance runners (LDR). These subjects received placebo or L-carnitine (2 g orally) during a 4-week period of training. Athletes receiving L-carnitine showed a dramatic increase (P < 0.001) in the PDH complex(More)
DSC is a general purpose tool that allows the distribution of a computation over a network of Unix workstations. Its control mechanisms automatically start up daemon processes on the participating workstations in order to communicate data by the standard IP/TCP/UDIP protocols. The user’s program distributes either remote procedure calls or source code of(More)
The aim of this study was to explore the possible involvement of the angiopoietin (Ang)-1, -2/Tie-2 system in the development, growth, and metastases evolution of gastroenteropancreatic-neuroendocrine tumors (GEP-NETs). We prospectively examined the serum levels of Tie-2, Ang-1, and Ang-2 by ELISA in 42 patients with proven GEP-NETs and 27 controls. We also(More)
The proliferation of general purpose mathematical software and specialized mathematical libraries has provided a wealth of computing resources for students, scientists, and engineers. The challenge remains to harness the power of these independent software tools within a single framework. OpenMath will provide formats and a protocol for the exchange of(More)
Indoleamine 2,3-dioxygenase (IDO) is an enzyme that depletes l-tryptophan, which provokes a decreased T cell response. This enzyme is expressed in human placenta, and can be also induced in many cell types such as monocytes, where endothelial (eNOS) and inducible (iNOS) nitric oxide synthases are also expressed. Previous studies have shown that nitric oxide(More)
New features of our DSC system for distributing a symbolic computation task over a network of processors are described. A new scheduler sends parallel subtasks to those compute nodes that are best suited in handling the added load of CPU usage and memory. Furthermore, a subtask can communicate back to the process that spawned it by a co-routine style(More)
The black box representation of a multivariate polynomial is a function that takes as input a value for each variable and then produces the value of the polynomial. We revisit the problem of computing the greatest common divisor (GCD) in black box format of several multivariate polynomials that themselves are given by black boxes. To this end an improved(More)