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OBJECTIVES/HYPOTHESIS To study by means of morphometric measurements the severity of vocal muscle atrophy in the elderly. STUDY DESIGN Cadaver study. SETTING Universidade Estadual Paulista (UNESP), Botucatu Medical School, Brazil. SUBJECTS AND METHODS Thirty vocal folds were collected from necropsies distributed into three groups: aged 60 to 75 years(More)
OBJECTIVES/HYPOTHESIS Vocal fold fibroblasts (VFF) are responsible for extracellular matrix synthesis supporting lamina propria in normal and diseased conditions. When tissue is injured, VFF become activated and differentiate into myofibroblasts to facilitate wound healing response. We investigated if vocal fold myofibroblasts can be utilized as surrogate(More)
INTRODUCTION Study the characteristics of pain vocal emission of newborns during venepuncture through acoustic analysis and relate it to NIPS pain scale and some variables of the newborns. METHODS Emissions of 111 healthy term newborns were recorded, whose lifetime varied from 24 to 72 h. The acoustic analysis was realized with GRAM 5.7 software verifying(More)
INTRODUCTION Vocal symptoms are common among the pediatric population and are often caused by vocal abuse. Laryngoscopy is essential for their diagnosis because it helps differentiate several laryngeal lesions, leading to a decision for suitable treatments considering each case. OBJECTIVES This study aims to present the clinical characteristics, and the(More)
Presbyphonia is a physiological process of aging voice that includes morphological changes in the coverage mucosa, muscle, and cartilage. We revised the morphological, endoscopic, and vocal acoustic changes that occur in presbyphonia and discussed some treatments proposed to minimize glottal incompetence and improve vocal performance of the elderly.
PURPOSE To investigate laryngeal and voice disorders in patients with gastroesophageal symptoms and their correlation with pH-monitoring. METHODS A prospective study was carried out in patients attended at the Voice Disorder Outpatient Clinics of Botucatu Medical School in a five-year period and had vocal and gastroesophagic symptoms. Patients underwent(More)
OBJECTIVE To assess the behavior of the immunoexpression of protein p53 in Reinke's edema and laryngeal squamous cell carcinoma. STUDY DESIGN retrospective. METHODS we recovered the histological paraffin blocks of patients who were subjected to Reinke's edema and laryngeal squamous cell carcinoma surgery in 2000-2011. The paraffin blocks were cut into(More)
OBJECTIVES To analyze the hyaluronic acid behavior in the lamina propria of the larynx with advancing age. STUDY DESIGN Prospective study. SETTING UNESP-Univ Estadual Paulista, Botucatu Medical School, Brazil. SUBJECTS AND METHODS Thirty vocal folds were obtained at necropsy from 10 adult males (30-50 years old) and 20 geriatric males (10: 60-75 years(More)
INTRODUCTION Psychogenic dysphonia is a functional disorder with variable clinical manifestations. OBJECTIVE To assess the clinical and vocal characteristics of patients with psychogenic dysphonia in a case series. METHODS The study included 28 adult patients with psychogenic dysphonia, evaluated at a University hospital in the last ten years. Assessed(More)
Common among children, vocal symptoms are a cause of concern for parents who seek elucidation of their diagnosis and treatment. Vocal nodules are the major cause of dysphonias in children and are related to vocal abuse. We conducted a literature review considering clinical, physiopathological, epidemiological, and histological aspects of vocal nodules, as(More)