Aneta Kubranska

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Previous studies have revealed that autism may arise as the result of exposure to high concentrations of prenatal testosterone. Ratio of second and fourth digits (2D:4D) is usually used as a proxy for prenatal testosterone. In this study, 2D:4D in 56 boys with ASD and in 32 control boys was measured. We found that the 2D:4D in ASD boys were lower than the(More)
Autism is one of the most genetically influenced neuropsychiatric disorders. However, its detailed genetic basis is far from being clear. Genome-wide association studies have revealed a number of candidate genes, mostly related to synaptogenesis and various neuroendocrine pathways. In our study we have focused on oxytocin (OT), oxytocin receptor (OXTR),(More)
OBJECTIVE Oxytocin (OT) has been implicated to play an important role in autism spectrum disorders (ASD) etiology. We aimed to find out the differences in plasma OT levels between children with autism and healthy children, the associations of OT levels with particular autism symptoms and the associations of particular parental autistic traits with their ASD(More)
INTRODUCTION Autism spectrum disorders (ASD) and hyperactivity symptoms exhibit an incidence that is male-biased. Thus androgen activity can be considered a plausible biological risk factor for these disorders. However, there is insufficient information about the association between increased androgen activity and hyperactivity symptoms in children with(More)
BACKGROUND Reelin plays an important role in the regulation of synaptic plasticity in adulthood. Administration of 5-metoxytryptamine (5MT), an agonist of serotonin receptors, during natal and neonatal periods results in decreased reelin expression. In adulthood, reelin is expressed by GABAergic neurons. OBJECTIVES The purpose of this study was to reveal(More)
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