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Combination therapy, or the use of multiple drugs, has been proven to be effective for complex diseases, but the differences in chemical properties and pharmacokinetics can be challenging in terms of the loading, delivering, and releasing multiple drugs. Here we demonstrate that we can load and selectively release two different DNA oligonucleotides from two(More)
Gold nanorods (GNRs) stabilized with cetyltrimethylammonium bromide (CTAB) and GNR functionalized via a ligand exchange method with either thiolated polyethylene glycol (PEG(5000)) or mercaptohexadecanoic acid (MHDA) were investigated for their stability in biological media and subsequent toxicological effects to HaCaT cells. GNR-PEG and GNR-MHDA exhibited(More)
Acknowledgements First and foremost, I would like to thank my advisor, Professor Mohammad Movassaghi for his advice, support, and guidance over the last six years. I am grateful to him for giving me the opportunity to work on challenging and rewarding projects in my graduate study. I would also like to thank members of my thesis committee, Professor Tim(More)
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