Andy F Wilderspin

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The interaction of DNA with partial dendrimers (dendritic polylysine containing seven lysines and eight terminal amino groups with or without a lipidic core) was studied. Compact complexes were formed which we term "dendriplexes". Agarose gel electrophoresis and exclusion of ethidium bromide confirmed the interaction. All the dendrons formed compact(More)
The cationic peptide dendrons synthesized and studied are lower generation polylysine-based partial dendrimers with or without lipid chains in the core. The dendrons with lipidic chains can be utilized as protein and liposomal mimics because of their unique structural properties. The full assignments of three different dendrons (L)7(NH2)8, (C14)1(L)7(NH2)8(More)
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